Endocrine Abstracts

Neuroprotection defines a set of homeostatic, self-repair mechanisms that probably evolved for the specially demanding conditions imposed by brain function. Among these, intercellular messengers such as the insulin-like growth factors (IGFs), that appeared very early during phylogeny, apparently play a prominent role despite their peripheral origin. In contrast to the heterogeneity seen in primitive organisms where at least 30 different IGF-like peptides are described, in mamm...